The information contained in the following drug guide is intended as an educational resource only. This guide is not exhaustive and does not contain all available information about this drug.This guide is not intended as medical advice for individual conditions or treatment.
The information provided in this guide does not replace the need for the advice and services of medical professionals or the need for medical examination. Always talk to your physician or pharmacist before taking any prescription medication or over the counter drugs (including any supplements) or before making any changes to your treatment. Only your doctor, nurse or pharmacist can provide you with safe and effective advice regarding your drug treatment.
The use of the information in this guide is at your sole risk. This information is provided "AS IS" with no warranties to accuracy or timeliness.
**All trademarks and registered trademarks are the property of their respective owners.
What is Desyrel?
Desyrel is an antidepressant that is prescribed to treat depression. Desyrel is thought to work by increasing the activity of certain chemicals in your brain which can help elevate your mood.
Key Facts About Desyrel
You should not take Desyrel if you are currently taking thioridazine (Mellaril), or an MAO inhibitor like furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate). You could suffer from a dangerous drug interaction if you take any of the above medications along with Desyrel.
When you first start taking Desyrel you may have thoughts about suicide, especially if you are younger than 24 years of age. You must tell your doctor if you have these thoughts, and be sure to keep regular appointments with your physician, particularly for the first 3 months of treatment.
If you have any new or worsening symptoms, like mood changes, panic attacks, trouble sleeping, impulsiveness, irritability, aggression, hyperactivity, or thoughts of suicide or harming yourself tell your doctor immediately.
You should avoid drinking alcohol while you are taking Desyrel.
Be aware that Desyrel may impair your reactions or thinking. You should be careful when driving or doing anything which requires you to be alert, especially when you first start Desyrel.
If you have a penis erection that is painful or lasts 6 hours or longer you should contact your doctor immediately. This is considered a medical emergency and may lead to a serious condition that must be corrected with surgery.
Tell your doctor if you are pregnant or plan to become pregnant. Desyrel is in FDA pregnancy category C. It is not known whether Desyrel will harm an unborn baby. It is known that Desyrel can pass into breast milk and may harm a nursing baby. Talk to your doctor before you start breast-feeding while taking Desyrel.
Desyrel should not be given to anyone younger than age 18.
Before You Take Desyrel
If you are allergic totrazodone you should not take Desyrel.
Tell your doctor if you are currently taking an MAO inhibitor like furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate). You will need to wait at least 14 days after stopping your MAO inhibitor before you can take Desyrel.
If you have bipolar disease, heart disease, liver disease or kidney disease you should talk to your doctor before taking Desyrel.
Tell your doctor before starting Desyrel if you have a history of drug abuse or suicidal thoughts.
You should inform your doctor if you have recently had a heart attack.
If you have a history of “Long QT syndrome” you should tell your doctor before starting treatment with Desyrel.
If you take medication for pain, arthritis, fever, or swelling like aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), indomethacin, piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and others you may have an increased risk of bruising or bleeding easily while taking Desyrel.
If you take medications that may make you sleepy like cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures or anxiety they can increase the sleepiness side effect from Desyrel.
Desyrel Drug Interactions
You should inform your doctor if you are taking any of the following:
antibiotics like clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), levofloxacin (Levaquin) and pentamidine (NebuPent, Pentam)
antidepressants or a medication to treat psychiatric disorders
antifungal medications like ketoconazole (Extina, Ketozole, Nizoral, Xolegal), itraconazole (Sporanox) and voriconazole (Vfend)
anti-malaria medications like chloroquine (Arelan) and mefloquine (Lariam)
heart or blood pressure medications like diltiazem (Cartia, Cardizem), nifedipine (Nifedical, Procardia) and verapamil (Calan, Covera, Isoptin, Verelan)
heart rhythm medications like amiodarone (Cordarone, Pacerone), disopyramide (Norpace), procainamide (Pronestyl) and quinidine (Quin-G)
HIV/AIDS medicine like fosamprenavir (Lexiva), indinavir (Crixivan) and ritonavir (Norvir)
methadone (Dolophine, Methadose)
ondansetron (Zofran)
seizure medications like carbamazepine (Carbatrol, Tegretol) or phenytoin (Dilantin)
sumatriptan (Imitrex)
Other drugs you take that are not listed may interact with Desyrel. You should tell your doctor about all of the medications you use. This includes prescription drugs, vitamins, supplements and herbal products, and over the counter medications. You should not begin taking a new medication without telling your doctor first.
Directions for Taking Desyrel
You should take Desyrel exactly as prescribed by your doctor. Do not take Desyrel in larger or smaller amounts, or for shorter or longer than recommended. Follow the directions on your prescription label.
You should take Desyrel at the same time every day.
Take Desyrel with a meal or a snack.
It may up to 2 weeks or longer before your symptoms improve while you are taking Desyrel. Continue using Desyrel as your doctor has directed you to do so. Do not stop using Desyrel without consulting your doctor, as you may experience adverse side effects if you stop taking this medication suddenly.
Desyrel needs to be stored at room temperature, and away from light, moisture and heat.
If you miss a dose of Desyrel you should attempt to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose do not take the missed dose in addition to your regular dose.
Desyrel Side Effects
If you experience any of the following adverse effects you should stop taking Desyrel and seek emergency medical help immediately:
aggressive, agitated or hostile behavior
allergic reaction such as breathing difficulties, hives, swelling of your face, lips, throat or tongue
anxiety or panic attacks
appetite loss
chest pain and heavy feeling with pain that spreads to your arm or shoulder and nausea, sweating plus a general ill feeling
confusion
depression that has increased
dizziness
erection or pain of penis for 6 hours or longer
faint feeling
fast or pounding heartbeat
hallucinations
headache, trouble concentrating and memory problems
seizures
shallow breathing
stiff or rigid muscles with a high fever, confusion, fast or uneven heartbeats, tremors and a feeling like you might pass out
suicidal thoughts or thought about hurting yourself
Less serious side effects of Desyrel may include:
blurry vision
constipation
drowsiness
headache
It should be noted that this is not a complete list of possible side effects of Desyrel. You should contact your physician for a complete list and medical advice regarding these effects.
Desyrel Description and Dosing
Desyrel is available as a 50 mg tablet. The 50 mg tablets are white, round, scored and debossed with PLIVA;433.
The dose of Desyrel is based on each individual. Your doctor will tell you what dose of Desyrel is right for you and will treat your condition effectively. Do not attempt to alter or change your dose without your physician’s consent.
If you suspect that you have overdosed with Desyrel you should seek emergency help immediately.
Ingredients in Desyrel
The primary active ingredient in Desyrel is trazodone hydrochloride. Inactive ingredients include colloidal silicon dioxide, anhydrous lactose, magnesium stearate, microcrystalline cellulose, and sodium starch glycolate.
The information contained in this drug guide is intended as an educational resource only. This guide is not exhaustive and does not contain all available information about this drug.This guide is not intended as medical advice for individual conditions or treatment.
The information provided in this guide does not replace the need for the advice and services of medical professionals or the need for medical examination. Always talk to your physician or pharmacist before taking any prescription medication or over the counter drugs (including any supplements) or before making any changes to your treatment. Only your doctor, nurse or pharmacist can provide you with safe and effective advice regarding your drug treatment.
The use of the information in this guide is at your sole risk. This information is provided "AS IS" with no warranties to accuracy or timeliness.
**All trademarks and registered trademarks are the property of their respective owners.
