Brand Name

Macrodantin {Procter & Gamble Pharmaceuticals, Inc.

Generic Name

nitrofurantoin, pronounced NYE troe fue RAN toin

---

Drug Guide

The information contained in the following drug guide is intended as an educational resource only. This guide is not exhaustive and does not contain all available information about this drug.This guide is not intended as medical advice for individual conditions or treatment.

The information provided in this guide does not replace the need for the advice and services of medical professionals or the need for medical examination. Always talk to your physician or pharmacist before taking any prescription medication or over the counter drugs (including any supplements) or before making any changes to your treatment. Only your doctor, nurse or pharmacist can provide you with safe and effective advice regarding your drug treatment.

The use of the information in this guide is at your sole risk. This information is provided "AS IS" with no warranties to accuracy or timeliness.

**All trademarks and registered trademarks are the property of their respective owners.

What is Macrodantin?

Macrodantin is an antibiotic prescribed to treat urinary tract infections caused by susceptible bacteria. This medication will not help if the cause of the infection is a virus.

Macrodantin may also be used for conditions that are not described in this medication guide.

Key Facts About Macrodantin

PREGANCY/BREASTFEEDING: Macrodantin is not known to harm an unborn baby, unless it is used during the last 2-4 weeks of your pregnancy. You should tell your doctor if you are pregnant, or if you plan to become pregnant before you start to take Macrodantin. You should not use Macrodantin without telling your doctor if you are breast-feeding a baby, as Macrodantin passes into breast milk and may increase the risks to your child.

Macrodantin may cause diarrhea during treatment. This may be a side effect or the sign of a possible new infection. If you have diarrhea that is watery or bloody, you should stop taking Macrodantin right away and call your doctor. Do not use any anti-diarrhea medications unless your doctor tells you to.

You should take Macrodantin with food, and avoid using antacids unless your doctor has instructed you to do so.

Before You Take Macrodantin

You should not use Macrodantin if you are allergic to nitrofurantoin.

Tell your doctor if you have kidney disease or a history of jaundice or liver problems caused by taking Macrodantin.

Let your doctor know if you are urinating less than usual or not at all before taking Macrodantin

Tell your doctor immediately if you have diabetes, anemia, an electrolyte imbalance, glucose-6-phosphate dehydrogenase (G6PD) deficiency, a vitamin B deficiency or a debilitating disease before starting treatment with Macrodantin.

Do not use Macrodantin if you are in the last 2 to 4 weeks of pregnancy.

You may need to have your blood tested while taking Macrodantin to be certain that Macrodantin is helping your condition if you take this medication long-term.

Macrodantin Drug Interactions

You should inform your doctor if you are taking any of the following:

• Topical lidocaine/prilocaine (Emla)
• choline magnesium salicylate (Tricosal, Trilisate)
• magnesium salicylate (Nuprin Backache, Doan’s Pills)
• probenecid (Benemid) or other gout medications

Other drugs you take that are not listed may interact with Macrodantin. You should tell your doctor about all of the medications you use. This includes prescription drugs, vitamins, supplements and herbal products, and over the counter medications. You should not begin taking a new medication without telling your doctor first.

Directions for Taking Macrodantin

You should take Macrodantin exactly as your doctor has prescribed you to. Do not use Macrodantin in larger or smaller amounts, or for shorter or longer than recommended. Follow the directions on your prescription label exactly.

Macrodantin is a medication that should be taken with a full 8 oz. glass of water.

You should take Macrodantin with food.

You must take Macrodantin for the full amount of time your doctor has prescribed for you to take it. Your symptoms may improve before the infection is completely cleared, but you still need to complete your course of antibiotic treatment. Failure to do so may result in an increased risk of further infections that are resistant to antibiotics.

Macrodantin can cause you to have unusual results with certain medical tests, including Urine Glucose tests. Let any doctor know that you seeing know you are taking Macrodantin.

If you miss a dose of Macrodantin you should attempt to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose do not take the missed dose in addition to your regular dose.

Macrodantin Side Effects

Seek immediate medical attention if you experience any of the following adverse effects and stop taking Macrodantin.

• allergic reaction that includes breathing difficulties, hives and swelling of your face, lips, throat or tongue
• clay colored stools
• confusion
• dark urine
• diarrhea that is watery or bloody
• easy bruising or paleness
• fever, chills and body aches with weight loss
• itching (severe)
• jaundice
• light headed and pale
• nausea
• red rash or patchy skin color with blistering
• severe headache with ear ringing, dizziness and vision problems
• peripheral neuropathy with symptoms like numbness, tingling, or pain in your hands or feet
• shortness of breath or chest pain, grey colored skin or blue colored nail beds
• stomach pain in upper stomach area and appetite loss
• weakness

Less serious Macrodantin side effects may include:

• diarrhea (mild)
• upset stomach
• urine that is rust colored or brown
• vaginal itching and discharge
• vomiting

It should be noted that this is not a complete list of possible side effects of Macrodantin. You should contact your physician for a complete list and medical advice regarding these effects.

Macrodantin Description and Dosing

Macrodantin is available as 25 mg, 50 mg and 100 mg capsules. The 25 mg capsules are opaque, white and imprinted with one black line encircling the capsule and coded “MACRODANTIN (nitrofurantoin macrocystals capsule) 25 mg” and “0149-0007.” The 50 mg capsules are opaque, yellow and white and imprinted with two black lines encircling the capsule and coded “MACRODANTIN (nitrofurantoin macrocystals capsule) 50 mg” and “0149-0008.” The 100 mg capsules are opaque, yellow and imprinted with three black lines encircling the capsule and coded “MACRODANTIN (nitrofurantoin macrocystals capsule) 100 mg” and “0149-0009.”.

Macrodantin dosages vary for each individual based on their age, condition and situation. Your doctor will tell you the right dose of Macrodantin for you to take. Do not change or alter your Macrodantin dose without talking to your doctor first.

If you suspect that you have overdosed with the Macrodantin you should seek emergency help immediately.

Ingredients in Macrodantin

Macrodantin contains the active ingredient nitrofurantoin macrocrystals. Capsules also contain the inactive ingredients edible black ink, gelatin, lactose, starch, talc, titanium dioxide, and may contain FD&C Yellow No. 6 and D&C Yellow No. 10.

Back to Top

The information contained in this drug guide is intended as an educational resource only. This guide is not exhaustive and does not contain all available information about this drug.This guide is not intended as medical advice for individual conditions or treatment.

The information provided in this guide does not replace the need for the advice and services of medical professionals or the need for medical examination. Always talk to your physician or pharmacist before taking any prescription medication or over the counter drugs (including any supplements) or before making any changes to your treatment. Only your doctor, nurse or pharmacist can provide you with safe and effective advice regarding your drug treatment.

The use of the information in this guide is at your sole risk. This information is provided "AS IS" with no warranties to accuracy or timeliness.

**All trademarks and registered trademarks are the property of their respective owners.