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Drug Guide

The information contained in the following drug guide is intended as an educational resource only. This guide is not exhaustive and does not contain all available information about this drug.This guide is not intended as medical advice for individual conditions or treatment.

The information provided in this guide does not replace the need for the advice and services of medical professionals or the need for medical examination. Always talk to your physician or pharmacist before taking any prescription medication or over the counter drugs (including any supplements) or before making any changes to your treatment. Only your doctor, nurse or pharmacist can provide you with safe and effective advice regarding your drug treatment.

The use of the information in this guide is at your sole risk. This information is provided "AS IS" with no warranties to accuracy or timeliness.

**All trademarks and registered trademarks are the property of their respective owners.

What is Renedil?

Renedil is a medication that is used to treat high blood pressure, or hypertension in adults. Renedil is in a class of medications called calcium channel blockers, and works by widening and relaxing your blood vessels to help improve your blood flow. Your doctor may prescribe Renedil for purposes not listed in this medication guide.

Key Facts About Renedil

Drinking alcohol can lower your blood pressure, which may increase certain side effects of Renedil. You should not drink alcohol while taking Renedil.

Renedil is a part of a complete program that your doctor has prescribed for you. This program includes diet, exercise, weight control, and possibly other medications. Follow your diet, medication, and exercise routines closely.

Renedil is in FDA pregnancy category C. We do not know if Renedil can harm an unborn baby. Tell your doctor if you are pregnant or if you plan to become pregnant before taking Renedil. It is not known that Renedil passes into breast milk and could cause harm to a nursing baby, so you should not breast-feed while you are taking Renedil.

Before You Take Renedil

You should not take Renedil if you are allergic to felodipine.

Before taking Renedil, tell your doctor if you have congestive heart failure, liver disease, kidney disease, low blood pressure or if you have recently had a heart attack.

While you are taking Renedil try to avoid getting up too fast from a sitting or lying position, as it may cause you to feel dizzy. Be cautious when getting up, and do so slowly to avoid falling.

Renedil Drug Interactions

You should inform your doctor if you are taking any of the following:

• antibiotics like clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole) and telithromycin (Ketek)
• antidepressants like nefazodone
• antifungal medications like itraconazole (Sporanox), ketoconazole (Extina, Ketozole, Nizoral, Xolegal), miconazole (Oravig) and voriconazole (Vfend)
• beta-blocker medications like Betapace, Blocadren, Corgard, Coreg, Inderal, InnoPran, Lopressor, Normodyne, Tenoretic, Tenormin, Toprol, Trandate and Zebeta
• cimetidine (Tagamet)
• conivaptan (Vaprisol)
• cyclosporine (Gengraf, Neoral, Sandimmune)
• heart or blood pressure medications like diltiazem (Cartia, Cardizem), nifedipine (Nifedical, Procardia) and verapamil (Calan, Covera, Isoptin, Verelan)
• HIV/AIDS medications like atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept) and ritonavir (Norvir, Kaletra)
• imatinib (Gleevec)
• isoniazid (for treating tuberculosis)
• seizure medications like carbamazepine (Carbatrol, Tegretol), phenobarbital (Solfoton), and phenytoin (Dilantin)
• tacrolimus (Prograf)

Other drugs you take that are not listed may interact with Renedil. You should tell your doctor about all of the medications you use. This includes prescription drugs, vitamins, supplements and herbal products, and over the counter medications. You should not begin taking a new medication without telling your doctor first.

Directions for Taking Renedil

Renedil should be taken once a day, with or without food.

You should take Renedil with a full glass of water.

Do not break, chew or crush the tablets. Swallow Renedil whole.

Grapefruit and grapefruit juice may interact with Renedil, which can lead to potentially serious effects. Discuss your use of grapefruit products with your doctor.

You should not drink alcohol while taking Renedil.

You should follow the instructions on your prescription label and not take Renedil for longer than recommended by your doctor, or in larger or smaller doses.

Renedil should be stored at room temperature, and away from both moisture and heat.

If you miss a dose of Renedil you should attempt to take the missed dose as soon as you remember within 12 hours of your scheduled dose. If it is more than 12 hours since your scheduled dose when you remember, do not take the missed dose but continue your next dose on schedule.

Renedil Side Effects

If you experience any of the following adverse effects you should seek emergency medical help immediately:

• breathing difficulties
• chest pain or heavy with pain spreading to the arm or shoulder and nausea, sweating plus a general ill feeling
• fainting
• Hives, swelling of your face, lips, throat, tongue, ankles, hands or feet
• Some side effects may occur when your first start using Renedil or if your dose is increased. These side effects are usually mild and should disappear shortly. Inform your doctor if they last longer than a week or if they are severe or uncomfortable.
• Swelling of ankles (mild);
• Flushing feeling or warmth;
• Dizziness;
• Pounding or racing heart;
• Headache;
• Unusual tiredness
• constipation
• diarrhea
• dizziness
• drowsiness
• headache
• insomnia
• joint pain
• headache
• muscle cramps
• nausea
• rash (mild) and warmth, redness or tingly feeling under skin
• restless or nervous
• sore throat or stuffy nose and cold symptoms
• stomach pain or upset stomach
• urinating more than normal
• weakness

It should be noted that this is not a complete list of possible side effects of Renedil. You should contact your physician for a complete list and medical advice regarding these effects.

Renedil Description and Dosing

Renedil is available as 2.5 mg, 5 mg and 10 mg tablets. The 2.5 mg dosage is yellow, circular, biconvex, film-coated and engraved ï on one side and 2.5 on the other side. The 5 mg dosage is pink, circular, film-coated, and engraved on one side and 5 on the other side. The 10 mg dosage is red-brown, circular, film-coated, and engraved ‘ on one side and 10 on the other side. All tablets are extended release.

You should consult your doctor for specific dosing pertaining to you. Do not attempt to alter or change your dose without your physician’s consent.

If you believe you may have overdosed with Renedil seek emergency medical help immediately.

Ingredients in Renedil

Renedil contains the active ingredient is felodipine. Inactive ingredients in the 2.5 mg tablets are aluminum silicate, hydroxypropyl cellulose, hydroxypropyl methylcellulose, lactose anhydrous, microcrystalline cellulose, polyoxy 40 hydrogenated castor oil, propyl gallate and sodium stearyl fumarate; coating layer: hydroxypropyl methylcellulose, polyethylene glycol, color titanium dioxide, color iron oxide yellow, carnauba wax and hydrogen peroxide. Inactive ingredients in the 5 mg tablets are aluminum silicate, hydroxypropyl cellulose hydroxypropyl methylcellulose, lactose anhydrous, microcrystalline cellulose, polyoxy 40 hydrogenated castor oil, propyl gallate and sodium stearyl fumarate; coating layer: hydroxypropyl methylcellulose, polyethylene glycol, color titanium dioxide, color iron oxide yellow, color iron oxide red-brown, carnauba wax and hydrogen peroxide. Inactive ingredients in the 10 mg tablets are aluminum silicate, hydroxypropyl cellulose, hydroxypropyl methylcellulose, lactose anhydrous, microcrystalline cellulose, polyoxy 40 hydrogenated castor oil, propyl gallate and sodium stearyl fumarate; coating layer: hydroxypropyl methylcellulose, polyethylene glycol, color titanium dioxide, color iron oxide yellow, color iron oxide red-brown, carnauba wax and hydrogen peroxide. All of the tablets are gluten- and tartrazine-free.

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The information contained in this drug guide is intended as an educational resource only. This guide is not exhaustive and does not contain all available information about this drug.This guide is not intended as medical advice for individual conditions or treatment.

The information provided in this guide does not replace the need for the advice and services of medical professionals or the need for medical examination. Always talk to your physician or pharmacist before taking any prescription medication or over the counter drugs (including any supplements) or before making any changes to your treatment. Only your doctor, nurse or pharmacist can provide you with safe and effective advice regarding your drug treatment.

The use of the information in this guide is at your sole risk. This information is provided "AS IS" with no warranties to accuracy or timeliness.

**All trademarks and registered trademarks are the property of their respective owners.