Zomig (zolmitriptan)

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Brand Name

Zomig {AstraZeneca}

Generic Name

zolmitriptan, pronounced ZOLE mi TRIP tan

Zolmitriptan (Zolmitriptan)

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Disclaimer

The information contained in this drug guide is intended as an educational resource only. This guide is not exhaustive and does not contain all available information about this drug.This guide is not intended as medical advice for individual conditions or treatment.

The information provided in this guide does not replace the need for the advice and services of medical professionals or the need for medical examination. Always talk to your physician or pharmacist before taking any prescription medication or over the counter drugs (including any supplements) or before making any changes to your treatment. Only your doctor, nurse or pharmacist can provide you with safe and effective advice regarding your drug treatment.

The use of the information in this guide is at your sole risk. This information is provided "AS IS" with no warranties to accuracy or timeliness.

**All trademarks and registered trademarks are the property of their respective owners.

 

What is Zomig?

Zomig is a medication used to treat migraine headaches that have already started. Zomig works by narrowing the blood vessels around the brain and reducing substances in your body that can trigger headache pain, sensitivity to light and sound, nausea and other migraine symptoms. Zomig will not prevent headaches or reduce the number of migraine headaches you have. Zomig may also be used for purposes that are not listed in this medication guide

 

Key Facts About Zomig

Zomig is not a treatment for a common tension headache, a headache that causes loss of movement on one side of your body, or a headache that seems to be different from your usual migraine headaches. You should only use Zomig if your doctor has confirmed that you suffer from migraine headaches and should take this medication.

Zomig will only treat a migraine headache that has already begun. It will not prevent migraine headaches or reduce the number of migraine headaches that you have.

You should not take Zomig within 24 hours before or after using another migraine headache medicine including: zolmitriptan nasal spray, almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt, Maxalt-MLT), sumatriptan (Imitrex, Treximet), ergot medications like ergotamine (Ergomar, Cafergot, Migergot), dihydroergotamine (D.H.E. 45, Migranal), or methylergonovine (Methergine).

If you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days you should not take Zomig.

Zomig is in FDA pregnancy category C. Taking Zomig during your pregnancy is not known to affect your unborn baby. Tell your doctor if you are pregnant or become pregnant while you are being treated with Zomig. We do not know if Zomig can pass into breast milk and harm a nursing baby. Do not use this medication without telling your doctor if you are breastfeeding a baby.

Zomig disintegrating tablets may contain phenylalanine. Tell your doctor before using this form of Zomig if you have phenylketonuria (PKU).

 

Before You Take Zomig

If you are allergic tozolmitriptan you should not take Zomig.

You should not take Zomig if you have coronary heart disease, angina, blood circulation problems, a lack of blood supply to your heart, severe or uncontrolled high blood pressure, a heart rhythm disorder, a history of heart disease, heart attack, or stroke (including “mini-strokes”).

Do not take Zomig if you have ischemic bowel disease.

You may not be a candidate to take Zomig if you have a headache that seems different from your usual migraine headaches.

If you have used an MAO inhibitor like furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days you should not take Zomig.

You should tell your doctor if you have kidney or liver disease before taking Zomig.

Tell your doctor if you have risk factors for coronary artery disease like diabetes, menopause, smoking, being overweight, having high cholesterol, having a family history of coronary artery disease, being older than 40 and a male, or being a female who has had a hysterectomy before taking Zomig.

 

Zomig Drug Interactions

Tell your doctor about all medications you use, especially:

  • antidepressant s like citalopram (Celexa), desvenlafaxine (Pristiq), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft) and venlafaxine (Effexor)
  • cimetidine (Tagamet)

Other drugs you may take and are not listed may interact with Zomig. You should tell your doctor about all of the medications you use. This includes prescription drugs, vitamins, supplements and herbal products, and over the counter medications. You should not begin taking a new medication without telling your doctor first.

 

Directions for Taking Zomig

Take Zomig exactly as your doctor has prescribed. Do not take Zomig in larger or smaller amounts or for longer or shorter than recommended. Follow the directions on your prescription label exactly.

You should take Zomig as soon as you have the first symptoms of a migraine headache.

If your headache does not completely go away, or goes away and comes back, after taking one tablet you may take a second tablet two (2) hours after the first tablet that you took. You should not take more than 10 mg of Zomig in a 24 hour period. If your symptoms have not improved after two doses of Zomig you should call your doctor.

Zomig is used as needed, and there is not a daily dosing schedule for you to follow. If you have more than four (4) headaches in one month (30 days) you should tell your doctor.

Zomig may be taken with or without food, but should be taken with a full glass of water if administered in tablet form.

If you are taking the orally disintegrating tablets Zomig-ZMT you should keep the tablet in its blister pack until you are ready to use it. When you are ready to take a tablet you should open the package carefully and peel back the foil from the tablet blister. You should not push a tablet through the foil or you may damage it. Be sure to use dry hands to remove the tablet and place it in your mouth. The tablet will start to dissolve right away. Allow the tablet to dissolve without chewing it. Swallow several times after the tablet has dissolved, or drink some water to be sure the contents of the tablet have been fully dissolved.

If you take Zomig long-term your doctor may want to check your heart function using an electrocardiograph or EKG to be sure that this medication is not harming your heart function. Be sure to keep regular appointments with your doctor while you are taking Zomig.

Zomig needs to be stored at room temperature, and away from light, moisture and heat.

 

Zomig Side Effects

If you experience any of the following adverse effects you should stop taking Zomig and seek emergency medical help immediately:

  • allergic reaction such as difficulty breathing, hives or swelling of your face, lips, tongue, or throat
  • antidepressant interactions (if you are taking an antidepressant) -agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination and fainting
  • chest pain or heavy feeling with pain spreading to your arm or shoulder, and nausea, sweating, or a general ill feeling
  • heartbeats that are fast or pounding with dizziness
  • jaw, neck or throat pain and tightness
  • numbness or weakness that Is sudden, especially on one side of your body
  • numbness or tingling with a pale or blue-colored appearance in your fingers or toes
  • severe headache along with confusion and problems with your vision, speech, or balance
  • stomach pain that is severe with bloody diarrhea

Less serious side effects of Zomig may include:

  • drowsiness
  • dry mouth
  • heavy feeling or pressure in any part of your body
  • neck or throat pain or pressure
  • tingly feeling under your skin with warmth or redness
  • upset stomach
  • weakness

It should be noted that this is not a complete list of possible side effects of Zomig. You should contact your physician for a complete list and medical advice regarding these effects.

 

Zomig Description and Dosing

Zomig is available in tablet form, in 2.5 mg and 5 mg strengths. Zomig is also available in orally disintegrating tablets in 2.5 mg and 5 mg strengths.

The 2.5 mg tablets are yellow, biconvex, round, film-coated, scored and have “Zomig” and “2.5” debossed on one side.

The 5 mg tablets are pink, biconvex, film-coated, and have “Zomig” and “5” debossed on one side.

The 2.5 mg Orally Disintegrating Tablets are white, flat faced, uncoated, beveled, and
debossed with a “Z” on one side.

The 5 mg Orally Disintegrating Tablets are white, flat faced, round, uncoated, beveled and debossed with a “Z” and “5” on one side.

If you suspect that you have overdosed with Zomig you should seek emergency help immediately.

 

Ingredients in Zomig

Zomig Tablets are available as 2.5 mg (yellow) and 5 mg (pink) film coated tablets for oral administration. The active ingredient in these tablets is zolmitriptan. The film coated tablets also contain the inactive ingredients anhydrous lactose NF, microcrystalline cellulose NF, sodium starch glycolate NF, magnesium stearate NF, hydroxypropyl methylcellulose USP, titanium dioxide USP, polyethylene glycol 400 NF, yellow iron oxide NF (2.5 mg tablet), red iron oxide NF (5 mg tablet), and polyethylene glycol 8000 NF.

Zomig-ZMT Orally Disintegrating Tablets are available as 2.5 mg and 5.0 mg white uncoated tablets for oral administration. The active ingredient in the ODT tablets is zolmitriptan. Other inactive ingredients include mannitol USP, microcrystalline cellulose NF, crospovidone NF, aspartame NF, sodium bicarbonate USP, citric acid anhydrous USP, colloidal silicon dioxide NF, magnesium stearate NF and orange flavor SN 027512.

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Disclaimer

The information contained in this drug guide is intended as an educational resource only. This guide is not exhaustive and does not contain all available information about this drug.This guide is not intended as medical advice for individual conditions or treatment.

The information provided in this guide does not replace the need for the advice and services of medical professionals or the need for medical examination. Always talk to your physician or pharmacist before taking any prescription medication or over the counter drugs (including any supplements) or before making any changes to your treatment. Only your doctor, nurse or pharmacist can provide you with safe and effective advice regarding your drug treatment.

The use of the information in this guide is at your sole risk. This information is provided "AS IS" with no warranties to accuracy or timeliness.

**All trademarks and registered trademarks are the property of their respective owners.